Semantic resources project/Antibodies/Revised Methods/Capillary Electrophoresis

Description
CE: Capillary Electrophoresis

Ontology Terms
MeSH: "Electrophoresis, Capillary"
 * D019075
 * http://bioportal.bioontology.org/visualize/40401/D019075
 * "A highly-sensitive (in the picomolar range, which is 10,000-fold more sensitive than conventional electrophoresis) and efficient technique that allows separation of PROTEINS; NUCLEIC ACIDS; and CARBOHYDRATES. (Segen, Dictionary of Modern Medicine, 1992)"

NCI Thesaurus: "Capillary Electrophoresis"
 * http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Capillary_Electrophoresis
 * http://bioportal.bioontology.org/visualize/40644/Capillary_Electrophoresis
 * "An electrophoresis procedure, in which a sample is introduced into a capillary tube and the components are separated by the application of high voltage. Due to the large surface to volume ratio, cooling is more efficient, allowing use of higher voltages. As a result, separation occurs more quickly and sensitivity is increased. The technique allows for separation of proteins, nucleic acids, and carbohydrates."

SNOMED Clinical Terms: "Capillary Electrophoresis"
 * 113068004
 * http://bioportal.bioontology.org/visualize/40403/113068004

Sample processing and separation techniques: "capillary electrophoresis"
 * sep:00140
 * http://bioportal.bioontology.org/visualize/39509/sep%253A00140
 * "Capillary electrophoresis is a protocol which can be used to separate ionic species by their charge and frictional forces. In traditional electrophoresis, electrically charged analytes move in a conductive liquid medium under the influence of an electric . Introduced in the 1960s, the technique of capillary electrophoresis (CE) was designed to separate species based on their size to charge ratio in the interior of a small capillary filled with an electrolyte."

Physico-chemical methods and properties: "capillary electrophoresis"
 * FIX:0000836
 * http://bioportal.bioontology.org/visualize/2991/FIX%253A0000836

Usage
Schaller, Hilder, and Haddad. Separation of antidepressants by capillary electrophoresis with in-line solid-phase extraction using a novel monolithic adsorbent. Analytica Chimica Acta 556:1,104-111 (January 2006) "'Several, extremely elegant electrophoresis-based pre-concentration techniques have been developed for CE [capillary electrophoresis] that allow sample enrichment up to three orders of magnitude. Unfortunately, these techniques all rely on exploiting differences, such as conductivity, between the sample and electrolyte composition and this can be problematic when complex sample matrices, such as biological samples which often contain high concentrations of salts and proteins are to be analysed.'"

Definition
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