Semantic resources project/Antibodies/Revised Methods/IFE

Description
IFE: Immunofixation Electrophoresis

Ontology Terms
SNOMED Clinical Terms: "Immunofixation Electrophoresis"
 * 69599001
 * http://bioportal.bioontology.org/visualize/40403/69599001

HL7 v3.0: "Immunofixation Electrophoresis (IFE)"
 * 0254
 * http://bioportal.bioontology.org/visualize/40392/0254

Usage
Jaskowski et al. Detection of {kappa} and {lambda} Light Chain Monoclonal Proteins in Human Serum: Automated Immunoassay versus Immunofixation Electrophoresis. Clinical and Vaccine Immunology 13:2,277-280 (February 2006) "'In our opinion, IFE remains the primary method for detecting and characterizing monoclonal proteins. Visualization of the serum kappa or lambda light chain on immunofixation electrophoresis is essential for making the initial diagnosis rather than measuring the kappa/lambda ratio. The FLC turbidimetric assays are likely of real value for detecting patients with pure light chain disease (which represents about 25% of monoclonal proteins) and may also be utilized for monitoring disease activity in those patients with light chain disease confirmed and characterized by IFE.'"

Definition
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