Semantic resources project/Antibodies/Revised Methods/Radio Immunoassay

Description
RIA: Radioimmunoassay

Outline
The issue here is that the immunogenic substance is the stuff that is labeled, not the antibody.

Ontology Terms
NCI Thesaurus: "Radioimmunoassay"
 * Radioimmunoassay
 * http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Radioimmunoassay
 * http://bioportal.bioontology.org/visualize/40377/Radioimmunoassay
 * "Radioimmunoassay (RIA) is an immunological technique, which quantitatively determines antigen and antibody concentrations, using a radioactively labeled substance (radioligand), either directly or indirectly."

SNOMED Clinical Terms: "Radioimmunoassay"
 * 4613005
 * http://bioportal.bioontology.org/visualize/40403/4613005

MeSH: "Radioimmunoassay"
 * D011863
 * http://bioportal.bioontology.org/visualize/40401/D011863
 * "Classic quantitative assay for detection of antigen-antibody reactions using a radioactively labeled substance (radioligand) either directly or indirectly to measure the binding of the unlabeled substance to a specific antibody or other receptor system. Non-immunogenic substances (e.g., haptens) can be measured if coupled to larger carrier proteins (e.g., bovine gamma-globulin or human serum albumin) capable of inducing antibody formation."

HL7v3.0: "Radioimmunoassay"
 * 0104
 * http://bioportal.bioontology.org/visualize/40392/0104

Definition
Adapted from MeSH: An immunoassay where the presence of a radioactively-labeled substance is detected by binding, either directly or indirectly, to an antibody.